Should the game end up being played in horrible conditions, then you can pretty much throw all of your handicapping studies out the window.
Bookmakers and bettors consider prop bets as an important part of watching - and enjoying - the Super Bowl.
Both teams feature some heavy hitters on the defensive end and the popular belief that the game is going to be a low-scoring affair.
Tom Brady and Peyton Manning have faced off 14 times in their careers with No. 12 sporting a 10-4 record against No. 18.
For a lot of sportsbooks, the Niners were the common denominator in a lot of parlays and teasers that were taken over the weekend.
It's NFL playoff time, which on most websites means some kind of preview of the four games with the author's gambling picks.
The Seattle Seahawks and the San Francisco 49ers enter as favorites against the New Orleans Saints and the Carolina Panthers.
Reche Caldwell and a handful of other individuals were charged with a variety of crimes including running an illegal gambling operation.
The New England Patriots and the Denver Broncos open as huge favorites against the Indianapolis Colts and the San Diego Chargers.
Wildcard Weekend kicks off the NFL Playoffs. Are you ready for some football?