Florida State is only a 1.5-point underdog, however, against the Eagles. Boston College is 7-1 ATS in its past eight on the road.
Week 10 around college football was one of the biggest of the season with a handful of games that were vital to the College Football Playoff picture.
Top-ranked Alabama looks nothing short of invincible this year and already has clinched a spot in the SEC Championship Game.
The first Saturday of November also is annually very important because it's when SEC West rivals LSU and Alabama face off in Baton Rouge.
Can the stigma of not being able to beat the Wolverines two biggest rivals: Michigan State and Ohio State be break by coach Jim Harbaugh?
The College Football Playoff outlook changed a bit over the weekend with No. 5 LSU, No. 7 Oklahoma and No. 8 Auburn all losing.
Week 5 of the college football season matchup is the ABC prime-time affair and likely Big Ten Game of the Year as No. 4 Ohio State visits No. 9 Penn State.
College football bettors don't have to wait until Saturday in Week 4 to wager on games involving ranked teams as there's a solid three-game Friday schedule.
The Buckeyes are -13 against the Frogs, and Ohio State has covered six of eight vs. Big 12 foes while UW is a 7-point favorite and Knights are -15.
The Cardinal are 4.5-point favorites despite going 0-2 against the Trojans last year, losing in Los Angeles and then in the Pac-12 title game.