The betting trends support backing the defending national champion Clemson Tigers (4-0) as solid road favorites in this Saturday’s ACC showdown against the Virginia Tech Hokies (4-0).
Odds courtesy of OddsShark.com
The Tigers opened as 7-point road chalk versus the Hokies, with their rout of the Louisville Cardinals two weeks ago away from home serving as a baseline for oddsmakers in setting this line.
Clemson was only a 3-point road favorite at Louisville and ended up crushing the home team 47-21 in an early statement game. The big question bettors need to consider heading into this matchup at Virginia Tech though is how the Hokies rank when compared to the Cardinals.
The Tigers came alive in the fourth quarter last week to beat the Boston College Eagles 34-7, but they still failed to cover the spread for the first time this season. Virginia Tech is 3-1 against the spread this year and may be getting more than a touchdown by 
the time this one kicks off, making the home dog a tempting play.
Other games involving Top 25 teams may see similar wagering opportunities, including the Tennessee Volunteers (3-1) hosting the Georgia Bulldogs (4-0) as 7.5-point home dogs.
The Vols edged the UMass Minutemen last week and lost to the Florida Gators in their previous game. But they will be out to prove the Bulldogs are not a Top 10 team, and they have gone 12-1 straight up in their last 13 home games and 4-1 ATS in the past five meetings.
Staying in the SEC, the Auburn Tigers (3-1) are nearing double-digit home favorites against the Mississippi State Bulldogs (3-1) and could close at -10 or higher before kickoff. Again, the dog has a favorable series trend in its favor, with Mississippi State covering four of the previous five meetings despite losing 12 of 16 SU in the matchup.
And the top-ranked Alabama Crimson Tide (4-0) will be trying to reverse an unfavorable series trend when they host the Ole Miss Rebels (2-1) as massive 27.5-point home chalk. The Crimson Tide could close at -28 or higher but have failed to cover the previous three meetings with the Rebels, who have won two of the last three SU.
